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CDNA highlights
Construction of DNA dolphins with flexible tails
Dolphins from the Aarhus University seal were constructed in DNA. The novel DNA structures are characterized by Atomic Force Microscopy (AFM) and shown to have flexible tails. The study involves the development of new software to design DNA-nanostructures of any shape and is expected to advance the field of DNA nanotechnology.
CDNA collaborator Hao Yan publishes the paper "Molecular robots guided by prescriptive landscapes". A molecular nanorobot dubbed a "spider" and labeled with green dyes traverses a substrate track built upon a DNA origami scaffold. It journeys towards its red-labeled goal by cleaving the visited substrates, thus exhibiting the characteristics of an autonomously moving, behavior-based robot at the molecular scale.
In the same issue of Nature DNA origami was used to create an assembly line for synthesizing gold nanoparticles.
This year’s Researchers Grand Prix (nicknamed Rock’n Research) held in Lille Vega on Tuesday 20 April was won by Kasper Jahn, PhD student at iNANO and CDNA.
In a review article in New Biotechnology Ebbe Sloth Andersen describes the computer tools available for prediction and design of DNA and RNA structures.
May 2010: DNA nano-spider published in Nature
March 2010: Tools for prediction and design