Publication - Toward reliable gold nanoparticle patterning on self-assembled DNA nanoscaffold

Toward reliable gold nanoparticle patterning on self-assembled DNA nanoscaffold

Research Area:	Organic Nanochemistry	Year:	2008
Type of Publication:	Article	Keywords:	DNA,chemistry Gold,chemistry Microscopy, Atomic Force Nanoparticles,chemistry ,Nanotechnology Surface Properties
Authors:	J. Sharma R. Chhabra C. S. Andersen K. V. Gothelf H. Yan Y. Liu
Journal:	J Am Chem Soc	Volume:	130
Number:	25	Pages:	7820-1


Note:
Jun 25
Abstract:
Assembly of gold nanoparticles (AuNP) into designer architectures with reliablity is important for nanophotonics and nanoelectronics applications. Toward this goal we present a new strategy to prepare AuNPs monofunctionalized with lipoic acid modified DNA oligos. This strategy offers increased bonding strength between DNA oligos and AuNP surface. These conjugates are further selectively mixed with other DNA strands and assembled into fixed sized DNA nanostructures carring a discrete number of AuNPs at desired positions. Atomic force microscopy imaging reveals a dramatically improved yield of the AuNPs on DNA tile structure compared to the ensembles using monothiolate AuNP-DNA conjugates.
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CDNA highlights

Seminar by Ned Seeman

On Friday the 9th of October 2009 professor Ned Seeman visited CDNA to give an iNANO lecture on "DNA: Not Merely the Secret of Life". Ned Seeman pioneered the field of structural DNA nanotechnology by suggesting and demonstrating DNA as a building block for nanoscale science. His group at NYU continues to contribute major advances to the field, recently, nanomechanical devices, DNA walkers, and DNA crystals.

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CDNA news

May 2010: DNA nano-spider published in Nature

CDNA collaborator Hao Yan publishes the paper "Molecular robots guided by prescriptive landscapes". A molecular nanorobot dubbed a "spider" and labeled with green dyes traverses a substrate track built upon a DNA origami scaffold. It journeys towards its red-labeled goal by cleaving the visited substrates, thus exhibiting the characteristics of an autonomously moving, behavior-based robot at the molecular scale.

In the same issue of Nature DNA origami was used to create an assembly line for synthesizing gold nanoparticles.