Highlights

Single-molecule chemical reactions on DNA origami

Researchers at the Danish National Research Foundation’s Centre for DNA Nanotechnology (CDNA) at iNANO demonstrate that it is possible to control chemical reactions on DNA nanostructures and generate images of reactions of individual molecules. The results were published on 28 February in Nature Nanotechnology. The article is available here

Seminar by Ned Seeman

On Friday the 9th of October 2009 professor Ned Seeman visited CDNA to give an iNANO lecture on "DNA: Not Merely the Secret of Life". Ned Seeman pioneered the field of structural DNA nanotechnology by suggesting and demonstrating DNA as a building block for nanoscale science. His group at NYU continues to contribute major advances to the field, recently, nanomechanical devices, DNA walkers, and DNA crystals.

DNA origami box with locks and keys

The DNA 'origami' method was extended into 3D to create an addressable DNA box on the nanometre scale that can be opened by externally supplied DNA 'keys'. The study appeared online in Nature, May 6, 2009.

dolphin

Construction of DNA dolphins with flexible tails

Dolphins from the Aarhus University seal were constructed in DNA. The novel DNA structures are characterized by Atomic Force Microscopy (AFM) and shown to have flexible tails. The study involves the development of new software to design DNA-nanostructures of any shape and is expected to advance the field of DNA nanotechnology.

CDNA highlights

Seminar by Ned Seeman

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CDNA news

May 2010: DNA nano-spider published in Nature

CDNA collaborator Hao Yan publishes the paper "Molecular robots guided by prescriptive landscapes". A molecular nanorobot dubbed a "spider" and labeled with green dyes traverses a substrate track built upon a DNA origami scaffold. It journeys towards its red-labeled goal by cleaving the visited substrates, thus exhibiting the characteristics of an autonomously moving, behavior-based robot at the molecular scale.

In the same issue of Nature DNA origami was used to create an assembly line for synthesizing gold nanoparticles.

April 2010: Kasper Jahn wins Rock n' Research

This year’s Researchers Grand Prix (nicknamed Rock’n Research) held in Lille Vega on Tuesday 20 April was won by Kasper Jahn, PhD student at iNANO and CDNA.

March 2010: Tools for prediction and design

In a review article in New Biotechnology Ebbe Sloth Andersen describes the computer tools available for prediction and design of DNA and RNA structures.

Read review - Browse tool table

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